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MSC Opera cruises

85 cruises sail aboard the MSC Opera, ranging from 3 to 25 nights. Prices start at $254. Most-visited destinations: Mediterranean (16), Other (8).

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Showing the first 24 of 85 sailings

  1. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Fri, Aug 14, 2026
    back Aug 24
    Length
    10 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,698per guestas of 5 days ago
    View sailing
  2. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sat, Aug 22, 2026
    back Sep 1
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,829per guestas of 10 days ago
    View sailing
  3. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Wed, Aug 26, 2026
    back Sep 5
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$2,234per guestas of 2 days ago
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  4. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Fri, Aug 28, 2026
    back Sep 7
    Length
    10 nights
    From Alicante
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Genoa (for Cinque Terre), Italy +2 more
    From$1,332per guestas of 17 hours ago
    View sailing
  5. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Tue, Sep 1, 2026
    back Sep 11
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,334per guestas of 17 hours ago
    View sailing
  6. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Sep 3, 2026
    back Sep 13
    Length
    10 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,574per guestas of 17 hours ago
    View sailing
  7. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sat, Sep 5, 2026
    back Sep 15
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$1,333per guestas of 10 days ago
    View sailing
  8. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Fri, Sep 11, 2026
    back Sep 21
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,341per guestas of 4 days ago
    View sailing
  9. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Tue, Sep 15, 2026
    back Sep 25
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$2,275per guestas of 17 hours ago
    View sailing
  10. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Fri, Sep 25, 2026
    back Oct 5
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$1,299per guestas of 17 hours ago
    View sailing
  11. MediterraneanMSC Cruises

    Western Mediterranean

    MSC Opera

    Departure
    Wed, Sep 30, 2026
    back Oct 10
    Length
    10 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,578per guestas of 17 hours ago
    View sailing
  12. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 1, 2026
    back Oct 10
    Length
    9 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +1 more
    From$669per guestas of 17 hours ago
    View sailing
  13. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Mon, Oct 5, 2026
    back Oct 10
    Length
    5 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Alicante
    From$434per guestas of 8 days ago
    View sailing
  14. MediterraneanMSC Cruises

    Western Mediterranean

    MSC Opera

    Departure
    Wed, Oct 7, 2026
    back Oct 10
    Length
    3 nights
    From Alicante
    Ports
    Olbia, Italy · Mahon, Spain
    From$280per guestas of 17 hours ago
    View sailing
  15. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 1
    Length
    3 nights
    From Civitavecchia (Rome)
    Ports
    Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy
    From$254per guestas of 17 hours ago
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  16. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 2
    Length
    4 nights
    From Civitavecchia (Rome)
    Ports
    Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy · Marseille (Provence), France
    From$426per guestas of 17 hours ago
    View sailing
  17. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 16
    Length
    18 nights
    From Civitavecchia (Rome)
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy +3 more
    From$935per guestas of 17 hours ago
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  18. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 23
    Length
    25 nights
    From Civitavecchia (Rome)
    Ports
    Bridgetown · La Romana, Dominican Republic · Fort De France · Barcelona (Tarragona), Spain · Tangier +9 more
    From$1,407per guestas of 1 month ago
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  19. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Fri, Oct 30, 2026
    back Nov 16
    Length
    17 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Livorno (for Florence/Pisa), Italy · Barcelona (Tarragona), Spain +2 more
    From$700per guestas of 17 hours ago
    View sailing
  20. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sat, Oct 31, 2026
    back Nov 16
    Length
    16 nights
    From Livorno (for Florence/Pisa), Italy
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Barcelona (Tarragona), Spain · Tangier +1 more
    From$969per guestas of 17 hours ago
    View sailing
  21. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sun, Nov 1, 2026
    back Nov 16
    Length
    15 nights
    From Marseille (Provence), France
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Barcelona (Tarragona), Spain · Tangier
    From$656per guestas of 17 hours ago
    View sailing
  22. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sun, Nov 1, 2026
    back Nov 20
    Length
    19 nights
    From Marseille (Provence), France
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Bridgetown · La Romana, Dominican Republic +3 more
    From$1,459per guestas of 17 hours ago
    View sailing
  23. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Mon, Nov 2, 2026
    back Nov 16
    Length
    14 nights
    From Barcelona (Tarragona), Spain
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · Tangier
    From$853per guestas of 17 hours ago
    View sailing
  24. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Mon, Nov 2, 2026
    back Nov 19
    Length
    17 nights
    From Barcelona (Tarragona), Spain
    Ports
    St. John's · Philipsburg · Basseterre, St. Kitts · La Romana, Dominican Republic · Catalina Island +1 more
    From$1,344per guestas of 17 hours ago
    View sailing
See all 85 sailings

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MSC Opera destinations