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MSC Opera cruises

78 cruises sail aboard the MSC Opera, ranging from 3 to 25 nights. Prices start at $225. Most-visited destinations: Mediterranean (18), Other (6).

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Showing the first 24 of 78 sailings

  1. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Tue, Jun 23, 2026
    back Jul 3
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,023per guestas of 4 hours ago
    View sailing
  2. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sat, Jun 27, 2026
    back Jul 7
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$959per guestas of 4 hours ago
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  3. MediterraneanMSC Cruises

    Western Mediterranean

    MSC Opera

    Departure
    Thu, Jul 2, 2026
    back Jul 12
    Length
    10 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,211per guestas of 4 hours ago
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  4. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Fri, Jul 3, 2026
    back Jul 13
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,219per guestas of 4 hours ago
    View sailing
  5. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Tue, Jul 7, 2026
    back Jul 17
    Length
    10 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Alicante · Genoa (for Cinque Terre), Italy +2 more
    From$2,001per guestas of 4 hours ago
    View sailing
  6. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Jul 9, 2026
    back Jul 19
    Length
    10 nights
    From Alicante
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Genoa (for Cinque Terre), Italy +2 more
    From$1,151per guestas of 4 hours ago
    View sailing
  7. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Wed, Jul 15, 2026
    back Jul 25
    Length
    10 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,495per guestas of 4 hours ago
    View sailing
  8. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sun, Jul 19, 2026
    back Jul 29
    Length
    10 nights
    From Alicante
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Genoa (for Cinque Terre), Italy +2 more
    From$2,953per guestas of 4 hours ago
    View sailing
  9. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Jul 23, 2026
    back Aug 2
    Length
    10 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$2,954per guestas of 4 hours ago
    View sailing
  10. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sat, Jul 25, 2026
    back Aug 4
    Length
    10 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$1,525per guestas of 4 hours ago
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  11. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Mon, Aug 24, 2026
    back Sep 3
    Length
    10 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$2,111per guestas of 4 hours ago
    View sailing
  12. MediterraneanMSC Cruises

    Western Mediterranean

    MSC Opera

    Departure
    Mon, Aug 31, 2026
    back Sep 10
    Length
    10 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$3,219per guestas of 4 hours ago
    View sailing
  13. MediterraneanMSC Cruises

    Western Mediterranean

    MSC Opera

    Departure
    Wed, Sep 30, 2026
    back Oct 10
    Length
    10 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +2 more
    From$2,542per guestas of 4 hours ago
    View sailing
  14. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 1, 2026
    back Oct 10
    Length
    9 nights
    From Marseille (Provence), France
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante +1 more
    From$739per guestas of 4 hours ago
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  15. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Sat, Oct 3, 2026
    back Oct 10
    Length
    7 nights
    From Malaga
    Ports
    Olbia, Italy · Mahon, Spain · Cadiz (Seville), Spain · Lisbon, Portugal · Alicante
    From$1,629per guestas of 4 hours ago
    View sailing
  16. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Mon, Oct 5, 2026
    back Oct 10
    Length
    5 nights
    From Lisbon, Portugal
    Ports
    Olbia, Italy · Mahon, Spain · Alicante
    From$424per guestas of 4 hours ago
    View sailing
  17. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 1
    Length
    3 nights
    From Civitavecchia (Rome)
    Ports
    Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy
    From$225per guestas of 4 hours ago
    View sailing
  18. MediterraneanMSC Cruises

    Mediterranean

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 2
    Length
    4 nights
    From Civitavecchia (Rome)
    Ports
    Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy · Marseille (Provence), France
    From$490per guestas of 4 hours ago
    View sailing
  19. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 16
    Length
    18 nights
    From Civitavecchia (Rome)
    Ports
    St. John's · Philipsburg · Basseterre · Genoa (for Cinque Terre), Italy · Livorno (for Florence/Pisa), Italy +3 more
    From$1,045per guestas of 4 hours ago
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  20. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Thu, Oct 29, 2026
    back Nov 23
    Length
    25 nights
    From Civitavecchia (Rome)
    Ports
    Bridgetown · La Romana · Fort De France · Barcelona (Tarragona), Spain · Tangier +9 more
    From$1,593per guestas of 4 hours ago
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  21. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Fri, Oct 30, 2026
    back Nov 16
    Length
    17 nights
    From Genoa (for Cinque Terre), Italy
    Ports
    St. John's · Philipsburg · Basseterre · Livorno (for Florence/Pisa), Italy · Barcelona (Tarragona), Spain +2 more
    From$936per guestas of 4 hours ago
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  22. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sat, Oct 31, 2026
    back Nov 16
    Length
    16 nights
    From Livorno (for Florence/Pisa), Italy
    Ports
    St. John's · Philipsburg · Basseterre · Barcelona (Tarragona), Spain · Tangier +1 more
    From$1,125per guestas of 4 hours ago
    View sailing
  23. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sun, Nov 1, 2026
    back Nov 16
    Length
    15 nights
    From Marseille (Provence), France
    Ports
    St. John's · Philipsburg · Basseterre · Barcelona (Tarragona), Spain · Tangier
    From$882per guestas of 4 hours ago
    View sailing
  24. OtherMSC Cruises

    MSC Grand Voyages

    MSC Opera

    Departure
    Sun, Nov 1, 2026
    back Nov 20
    Length
    19 nights
    From Marseille (Provence), France
    Ports
    St. John's · Philipsburg · Basseterre · Bridgetown · La Romana +3 more
    From$1,554per guestas of 4 hours ago
    View sailing
See all 78 sailings

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