CruiseGrid

Cruises from La Romana

38 cruises depart La Romana, ranging from 3 to 14 nights. Prices start at $179. Most-visited destinations: Caribbean (24).

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Showing the first 24 of 38 sailings

  1. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Nov 16, 2026
    back Nov 19
    Length
    3 nights
    From La Romana, Dominican Republic
    Ports
    Catalina Island
    From$179per guestas of 2 hours ago
    View sailing
  2. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Nov 16, 2026
    back Nov 20
    Length
    4 nights
    From La Romana, Dominican Republic
    Ports
    Bridgetown · Catalina Island
    From$329per guestas of 2 hours ago
    View sailing
  3. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Nov 23, 2026
    back Nov 30
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Samana Bay, Dominican Republic · Catalina Island
    From$749per guestas of 2 hours ago
    View sailing
  4. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Nov 30, 2026
    back Dec 7
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Road Town (Tortola), British Virgin Islands · Bridgetown · Catalina Island · Fort De France · Pointe-a-Pitre, Guadeloupe
    From$709per guestas of 2 months ago
    View sailing
  5. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Dec 7, 2026
    back Dec 14
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Road Town (Tortola), British Virgin Islands · Catalina Island
    From$419per guestas of 3 months ago
    View sailing
  6. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Dec 14, 2026
    back Dec 21
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Road Town (Tortola), British Virgin Islands · Bridgetown · Catalina Island · Fort De France · Pointe-a-Pitre, Guadeloupe
    From$559per guestas of 2 hours ago
    View sailing
  7. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 4, 2027
    back Jan 11
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Samana Bay, Dominican Republic · Catalina Island
    From$599per guestas of 1 month ago
    View sailing
  8. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 11, 2027
    back Jan 18
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Virgin Gorda, Virgin Islands · Bridgetown · Catalina Island · Fort De France
    From$629per guestas of 2 hours ago
    View sailing
  9. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 11, 2027
    back Jan 25
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Bridgetown +4 more
    From$1,390per guestas of 2 hours ago
    View sailing
  10. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 18, 2027
    back Jan 25
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Samana Bay, Dominican Republic · Catalina Island
    From$589per guestas of 2 hours ago
    View sailing
  11. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 18, 2027
    back Feb 1
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · St. John's · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Road Town (Tortola), British Virgin Islands +5 more
    From$1,390per guestas of 2 hours ago
    View sailing
  12. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 25, 2027
    back Feb 1
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Road Town (Tortola), British Virgin Islands · Bridgetown · Catalina Island · Fort De France
    From$467per guestas of 1 month ago
    View sailing
  13. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Jan 25, 2027
    back Feb 8
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Road Town (Tortola), British Virgin Islands · Basseterre, St. Kitts +4 more
    From$1,350per guestas of 2 hours ago
    View sailing
  14. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Feb 1, 2027
    back Feb 15
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Road Town (Tortola), British Virgin Islands · Bridgetown +4 more
    From$1,380per guestas of 2 hours ago
    View sailing
  15. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Feb 8, 2027
    back Feb 22
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Road Town (Tortola), British Virgin Islands · Basseterre, St. Kitts · Bridgetown +4 more
    From$1,340per guestas of 2 hours ago
    View sailing
  16. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Feb 15, 2027
    back Feb 22
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Road Town (Tortola), British Virgin Islands · Catalina Island
    From$540per guestas of 2 months ago
    View sailing
  17. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Feb 22, 2027
    back Mar 1
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Road Town (Tortola), British Virgin Islands · Bridgetown · Catalina Island · Fort De France
    From$574per guestas of 2 months ago
    View sailing
  18. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Mar 8, 2027
    back Mar 15
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    St. John's · Road Town (Tortola), British Virgin Islands · Bridgetown · Catalina Island · Fort De France
    From$599per guestas of 2 hours ago
    View sailing
  19. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Mar 15, 2027
    back Mar 22
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Road Town (Tortola), British Virgin Islands · Catalina Island
    From$546per guestas of 2 hours ago
    View sailing
  20. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Mar 29, 2027
    back Apr 5
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · St. John's · Virgin Gorda, Virgin Islands · Basseterre, St. Kitts · Catalina Island
    From$709per guestas of 2 hours ago
    View sailing
  21. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Apr 5, 2027
    back Apr 12
    Length
    7 nights
    From La Romana, Dominican Republic
    Ports
    Catalina Island · Oranjestad, Aruba · Saint George, Grenada · Willemstad · Kralendijk, Bonaire
    From$769per guestas of 2 hours ago
    View sailing
  22. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Apr 12, 2027
    back Apr 15
    Length
    3 nights
    From La Romana, Dominican Republic
    Ports
    Catalina Island
    From$179per guestas of 2 hours ago
    View sailing
  23. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Apr 12, 2027
    back Apr 16
    Length
    4 nights
    From La Romana, Dominican Republic
    Ports
    Bridgetown · Catalina Island
    From$269per guestas of 2 hours ago
    View sailing
  24. CaribbeanMSC Cruises

    Southern Caribbean

    MSC Opera

    Departure
    Mon, Apr 12, 2027
    back Apr 26
    Length
    14 nights
    From La Romana, Dominican Republic
    Ports
    Philipsburg, St. Maarten · St. John's · Virgin Gorda, Virgin Islands · Road Town (Tortola), British Virgin Islands · Bridgetown +4 more
    From$4,643per guestas of 2 hours ago
    View sailing
See all 38 sailings

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