MexicoRoyal Caribbean International
Ensenada Cruise
Serenade of the Seas
- Departure
- Fri, Oct 2, 2026
- back Oct 4
- Length
- 2 nights
- From San Diego
- Ports
- Ensenada
From$311per guestas of 14 hours ago
View sailingCruises from San Diego
132 cruises depart San Diego, ranging from 2 to 35 nights. Prices start at $311. Most-visited destinations: Mexico (17), Hawaii (3), Panama Canal (2).
Showing the first 24 of 132 sailings
- Panama CanalHolland America Line
16-DAY PANAMA CANAL
Nieuw Amsterdam
- Departure
- Fri, Oct 2, 2026
- back Oct 18
- Length
- 16 nights
- From San Diego
From$1,599per guestas of 16 seconds agoView sailing - OtherMSC Cruises
MSC Grand Voyages
MSC Poesia
- Departure
- Sat, Oct 3, 2026
- back Oct 17
- Length
- 14 nights
- From San Diego
- Ports
- Puntarenas · Cartagena, Spain · Colon · Cruising Panama Canal · Cabo San Lucas, Mexico +1 more
From$1,057per guestas of 1 day agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & La Paz Cruise
Serenade of the Seas
- Departure
- Sun, Oct 4, 2026
- back Oct 11
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · La Paz
From$508per guestas of 14 hours agoView sailing - MexicoHolland America Line
7-DAY MEXICAN RIVIERA
Zaandam
- Departure
- Thu, Oct 8, 2026
- back Oct 15
- Length
- 7 nights
- From San Diego
From$1,098per guestas of 3 hours agoView sailing - Panama CanalHolland America Line
16-DAY PANAMA CANAL
Eurodam
- Departure
- Thu, Oct 8, 2026
- back Oct 24
- Length
- 16 nights
- From San Diego
From$1,799per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Catalina & Ensenada Cruise
Serenade of the Seas
- Departure
- Sun, Oct 11, 2026
- back Oct 15
- Length
- 4 nights
- From San Diego
- Ports
- Catalina Island · Ensenada
From$396per guestas of 14 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada Cruise
Serenade of the Seas
- Departure
- Thu, Oct 15, 2026
- back Oct 18
- Length
- 3 nights
- From San Diego
- Ports
- Ensenada
From$362per guestas of 14 hours agoView sailing - HawaiiHolland America Line
35-DAY LEGENDARY HAWAII, TAHITI & MARQUESAS
Zaandam
- Departure
- Thu, Oct 15, 2026
- back Nov 19
- Length
- 35 nights
- From San Diego
From$5,026per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & La Paz Cruise
Serenade of the Seas
- Departure
- Sun, Oct 18, 2026
- back Oct 25
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · La Paz
From$557per guestas of 14 hours agoView sailing - MexicoHolland America Line
11-DAY MEXICAN RIVIERA & SEA OF CORTEZ
Koningsdam
- Departure
- Tue, Oct 20, 2026
- back Oct 31
- Length
- 11 nights
- From San Diego
From$1,184per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & La Paz Cruise
Serenade of the Seas
- Departure
- Sun, Oct 25, 2026
- back Nov 1
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · La Paz
From$499per guestas of 14 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & Mazatlan Cruise
Serenade of the Seas
- Departure
- Sun, Nov 1, 2026
- back Nov 8
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · Mazatlan
From$492per guestas of 14 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & Mazatlan Cruise
Serenade of the Seas
- Departure
- Sun, Nov 8, 2026
- back Nov 15
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · Mazatlan
From$513per guestas of 14 hours agoView sailing - Pacific NorthwestHolland America Line
7-DAY CLASSIC CALIFORNIA COAST
Koningsdam
- Departure
- Sat, Nov 14, 2026
- back Nov 21
- Length
- 7 nights
- From San Diego
From$793per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada, Cabo & La Paz Cruise
Serenade of the Seas
- Departure
- Sun, Nov 15, 2026
- back Nov 22
- Length
- 7 nights
- From San Diego
- Ports
- Ensenada · Cabo San Lucas · La Paz
From$511per guestas of 14 hours agoView sailing - HawaiiHolland America Line
18-DAY CIRCLE HAWAII HOLIDAY
Zaandam
- Departure
- Thu, Nov 19, 2026
- back Dec 7
- Length
- 18 nights
- From San Diego
From$1,599per guestas of 3 hours agoView sailing - HawaiiHolland America Line
30-DAY CIRCLE HAWAII & SEA OF CORTEZ
Zaandam
- Departure
- Thu, Nov 19, 2026
- back Dec 19
- Length
- 30 nights
- From San Diego
From$3,025per guestas of 3 hours agoView sailing - MexicoHolland America Line
7-DAY BAJA PENINSULA
Koningsdam
- Departure
- Sat, Nov 21, 2026
- back Nov 28
- Length
- 7 nights
- From San Diego
From$834per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Cabo, Mazatlan & La Paz
Serenade of the Seas
- Departure
- Sun, Nov 22, 2026
- back Nov 29
- Length
- 7 nights
- From San Diego
- Ports
- Cabo San Lucas · Mazatlan · La Paz
From$862per guestas of 14 hours agoView sailing - MexicoHolland America Line
10-DAY MEXICAN RIVIERA & SEA OF CORTEZ
Koningsdam
- Departure
- Sat, Nov 28, 2026
- back Dec 8
- Length
- 10 nights
- From San Diego
From$809per guestas of 3 hours agoView sailing - MexicoRoyal Caribbean International
Catalina & Ensenada Cruise
Serenade of the Seas
- Departure
- Sun, Nov 29, 2026
- back Dec 3
- Length
- 4 nights
- From San Diego
- Ports
- Catalina Island · Ensenada
From$362per guestas of 14 hours agoView sailing - MexicoRoyal Caribbean International
Ensenada Cruise
Serenade of the Seas
- Departure
- Thu, Dec 3, 2026
- back Dec 6
- Length
- 3 nights
- From San Diego
- Ports
- Ensenada
From$322per guestas of 14 hours agoView sailing - MexicoRoyal Caribbean International
Catalina & Ensenada Cruise
Serenade of the Seas
- Departure
- Sun, Dec 6, 2026
- back Dec 10
- Length
- 4 nights
- From San Diego
- Ports
- Catalina Island · Ensenada
From$362per guestas of 14 hours agoView sailing