CruiseGrid
Showing 73–96 of 112 sailings
Booking links are affiliate — we may earn a commission at no extra cost to you.
  1. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Wed, Oct 13, 2027
    back Oct 29
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas · Fuerte Amador, Panama (for Panama City) +2 more
    From$1,779per guestas of 12 hours ago
    View sailing
  2. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Emerald Princess

    Departure
    Sun, Oct 24, 2027
    back Nov 9
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas · Fuerte Amador, Panama (for Panama City) +2 more
    From$1,419per guestas of 12 hours ago
    View sailing
  3. Panama CanalCarnival Cruise Line

    10-Day Caribbean & Panama from Galveston, TX

    Carnival Spirit

    Departure
    Mon, Oct 25, 2027
    back Nov 4
    Length
    10 nights
    From Galveston, TX
    Ports
    Cozumel · Limon, Costa Rica · Colón, Panama
    From$1,007per guestas of 12 hours ago
    View sailing
  4. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Thu, Nov 11, 2027
    back Nov 23
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +2 more
    From$1,584per guestas of 12 hours ago
    View sailing
  5. Panama CanalCarnival Cruise Line

    10-Day Caribbean & Panama from Galveston, TX

    Carnival Sunshine

    Departure
    Mon, Nov 22, 2027
    back Dec 2
    Length
    10 nights
    From Galveston, TX
    Ports
    Isla Tropicale, Roatan · Colón, Panama · Limon, Costa Rica
    From$959per guestas of 12 hours ago
    View sailing
  6. Panama CanalCelebrity Cruises

    Panama Canal & Southern Caribbean

    Celebrity Ascent

    Departure
    Mon, Nov 22, 2027
    back Dec 3
    Length
    11 nights
    From Fort Lauderdale
    Ports
    Oranjestad · Willemstad · Panama Canal (Cruising) · George Town · Bimini
    From$1,912per guestas of 13 hours ago
    View sailing
  7. Panama CanalCarnival Cruise Line

    14-Day Caribbean & Panama from New Orleans, LA

    Carnival Liberty

    Departure
    Sun, Nov 28, 2027
    back Dec 12
    Length
    14 nights
    From New Orleans, LA
    Ports
    Montego Bay · Aruba · Curaçao · Cartagena, Spain · Colón, Panama +1 more
    From$1,300per guestas of 12 hours ago
    View sailing
  8. Panama CanalCarnival Cruise Line

    8-Day Caribbean & Panama from Tampa, FL

    Carnival Spirit

    Departure
    Sat, Dec 4, 2027
    back Dec 12
    Length
    8 nights
    From Tampa, FL
    Ports
    Limon, Costa Rica · Colón, Panama
    From$916per guestas of 12 hours ago
    View sailing
  9. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean Holiday

    Island Princess

    Departure
    Mon, Dec 13, 2027
    back Dec 29
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas · Puerto Chiapas, Mexico +2 more
    From$1,399per guestas of 12 hours ago
    View sailing
  10. Panama CanalCarnival Cruise Line

    8-Day Caribbean & Panama from Tampa, FL

    Carnival Spirit

    Departure
    Sat, Dec 18, 2027
    back Dec 26
    Length
    8 nights
    From Tampa, FL
    Ports
    Limon, Costa Rica · Colón, Panama
    From$1,197per guestas of 12 hours ago
    View sailing
  11. Panama CanalHolland America Line

    15-DAY PANAMA CANAL HOLIDAY

    Zaandam

    Departure
    Sat, Dec 18, 2027
    back Jan 2
    Length
    15 nights
    From San Diego
    From$2,674per guestas of 11 hours ago
    View sailing
  12. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean Holiday

    Caribbean Princess

    Departure
    Thu, Dec 23, 2027
    back Jan 4
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,694per guestas of 12 hours ago
    View sailing
  13. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean Holiday

    Island Princess

    Departure
    Wed, Dec 29, 2027
    back Jan 14
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas · Fuerte Amador, Panama (for Panama City) +2 more
    From$1,599per guestas of 12 hours ago
    View sailing
  14. Panama CanalCarnival Cruise Line

    10-Day Caribbean & Panama from Galveston, TX

    Carnival Sunshine

    Departure
    Mon, Jan 3, 2028
    back Jan 13
    Length
    10 nights
    From Galveston, TX
    Ports
    Cozumel · Limon, Costa Rica · Colón, Panama
    From$851per guestas of 12 hours ago
    View sailing
  15. Panama CanalCelebrity Cruises

    Panama Canal & Southern Caribbean

    Celebrity Ascent

    Departure
    Mon, Jan 3, 2028
    back Jan 14
    Length
    11 nights
    From Fort Lauderdale
    Ports
    Oranjestad · Willemstad · Panama Canal (Cruising) · George Town · Bimini
    From$2,215per guestas of 13 hours ago
    View sailing
  16. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Fri, Jan 14, 2028
    back Jan 30
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas · Puerto Chiapas, Mexico +2 more
    From$1,574per guestas of 12 hours ago
    View sailing
  17. Panama CanalHolland America Line

    14-DAY PANAMA CANAL

    Zaandam

    Departure
    Sun, Jan 16, 2028
    back Jan 30
    Length
    14 nights
    From Fort Lauderdale
    From$2,634per guestas of 11 hours ago
    View sailing
  18. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Sun, Jan 30, 2028
    back Feb 15
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas · Fuerte Amador, Panama (for Panama City) +2 more
    From$1,474per guestas of 12 hours ago
    View sailing
  19. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Sat, Feb 12, 2028
    back Feb 24
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +2 more
    From$1,489per guestas of 12 hours ago
    View sailing
  20. Panama CanalCarnival Cruise Line

    10-Day Caribbean & Panama from Galveston, TX

    Carnival Sunshine

    Departure
    Mon, Feb 14, 2028
    back Feb 24
    Length
    10 nights
    From Galveston, TX
    Ports
    Cozumel · Limon, Costa Rica · Colón, Panama
    From$901per guestas of 12 hours ago
    View sailing
  21. Panama CanalCelebrity Cruises

    Panama Canal & Southern Caribbean

    Celebrity Ascent

    Departure
    Mon, Feb 14, 2028
    back Feb 25
    Length
    11 nights
    From Fort Lauderdale
    Ports
    Oranjestad · Oranjestad · Willemstad · Panama Canal (Cruising) · George Town
    From$2,407per guestas of 13 hours ago
    View sailing
  22. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Tue, Feb 15, 2028
    back Mar 2
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas · Puerto Chiapas, Mexico +2 more
    From$1,444per guestas of 12 hours ago
    View sailing
  23. Panama CanalCarnival Cruise Line

    8-Day Caribbean & Panama from Tampa, FL

    Carnival Spirit

    Departure
    Sat, Feb 26, 2028
    back Mar 5
    Length
    8 nights
    From Tampa, FL
    Ports
    Limon, Costa Rica · Colón, Panama
    From$978per guestas of 12 hours ago
    View sailing
  24. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Thu, Mar 2, 2028
    back Mar 18
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Quetzal, Guatemala · Puntarenas · Fuerte Amador, Panama (for Panama City) +2 more
    From$1,704per guestas of 12 hours ago
    View sailing