CruiseGrid
Showing 25–48 of 138 sailings
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  1. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean Holiday

    Island Princess

    Departure
    Sat, Dec 12, 2026
    back Dec 28
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas, Costa Rica · Puerto Chiapas, Mexico +2 more
    From$1,449per guestas of 4 hours ago
    View sailing
  2. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean Holiday

    Caribbean Princess

    Departure
    Thu, Dec 17, 2026
    back Dec 29
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,094per guestas of 4 hours ago
    View sailing
  3. Panama CanalHolland America Line

    15-DAY PANAMA CANAL HOLIDAY

    Zaandam

    Departure
    Sat, Dec 19, 2026
    back Jan 3
    Length
    15 nights
    From San Diego, California
    From$1,887per guestas of 4 hours ago
    View sailing
  4. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean Holiday

    Island Princess

    Departure
    Mon, Dec 28, 2026
    back Jan 13
    Length
    16 nights
    From Los Angeles, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Chiapas, Mexico · Puntarenas, Costa Rica · Fuerte Amador, Panama (for Panama City) +2 more
    From$2,969per guestas of 4 hours ago
    View sailing
  5. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean Holiday

    Caribbean Princess

    Departure
    Tue, Dec 29, 2026
    back Jan 10
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,094per guestas of 4 hours ago
    View sailing
  6. Panama CanalHolland America Line

    14-DAY PANAMA CANAL

    Zuiderdam

    Departure
    Sat, Jan 2, 2027
    back Jan 16
    Length
    14 nights
    From Miami, FL
    From$1,475per guestas of 4 hours ago
    View sailing
  7. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Coral Princess

    Departure
    Wed, Jan 6, 2027
    back Jan 21
    Length
    15 nights
    From Ft. Lauderdale, Florida
    Ports
    Cartagena, Spain · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas, Costa Rica · Puerto Chiapas, Mexico +2 more
    From$1,702per guestas of 4 hours ago
    View sailing
  8. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Coral Princess

    Departure
    Wed, Jan 6, 2027
    back Jan 29
    Length
    23 nights
    From Ft. Lauderdale, Florida
    Ports
    Cartagena, Spain · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas, Costa Rica · Puerto Chiapas, Mexico +5 more
    Pricing not availableCheck cruise line for live ratesas of 4 hours ago
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  9. Panama CanalHolland America Line

    21-DAY SOUTHERN CARIBBEAN & PANAMA CANAL: ABC ISLANDS

    Nieuw Amsterdam

    Departure
    Fri, Jan 8, 2027
    back Jan 29
    Length
    21 nights
    From Fort Lauderdale
    From$2,421per guestas of 4 hours ago
    View sailing
  10. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Sun, Jan 10, 2027
    back Jan 22
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Curacao · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,024per guestas of 4 hours ago
    View sailing
  11. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Wed, Jan 13, 2027
    back Jan 29
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas, Costa Rica · Puerto Chiapas, Mexico +2 more
    From$3,549per guestas of 4 hours ago
    View sailing
  12. Panama CanalCarnival Cruise Line

    8-Day Caribbean & Panama from Tampa, FL

    Carnival Legend

    Departure
    Sat, Jan 16, 2027
    back Jan 24
    Length
    8 nights
    From Tampa, FL
    Ports
    Limon, Costa Rica · Colón, Panama
    From$1,044per guestas of 4 hours ago
    View sailing
  13. Panama CanalHolland America Line

    12-DAY PANAMA CANAL DISCOVERY: COSTA RICA & GREATER ANTILLES

    Nieuw Amsterdam

    Departure
    Sun, Jan 17, 2027
    back Jan 29
    Length
    12 nights
    From Fort Lauderdale
    From$1,676per guestas of 4 hours ago
    View sailing
  14. Panama CanalHolland America Line

    21-DAY PANAMA CANAL & EASTERN CARIBBEAN: U.S. VIRGIN ISLANDS

    Nieuw Amsterdam

    Departure
    Sun, Jan 17, 2027
    back Feb 7
    Length
    21 nights
    From Fort Lauderdale
    From$2,388per guestas of 4 hours ago
    View sailing
  15. Panama CanalCarnival Cruise Line

    10-Day Caribbean & Panama from Galveston, TX

    Carnival Miracle

    Departure
    Mon, Jan 18, 2027
    back Jan 28
    Length
    10 nights
    From Galveston, TX
    Ports
    Cozumel · Limon, Costa Rica · Colón, Panama
    From$950per guestas of 4 hours ago
    View sailing
  16. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Fri, Jan 22, 2027
    back Feb 3
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$954per guestas of 4 hours ago
    View sailing
  17. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Fri, Jan 29, 2027
    back Feb 14
    Length
    16 nights
    From San Diego, California
    Ports
    Puerto Vallarta · Huatulco, Mexico · Puerto Chiapas, Mexico · Puntarenas, Costa Rica · Fuerte Amador, Panama (for Panama City) +2 more
    From$2,189per guestas of 4 hours ago
    View sailing
  18. Panama CanalHolland America Line

    21-DAY EASTERN CARIBBEAN & PANAMA CANAL: U.S. VIRGIN ISLANDS

    Nieuw Amsterdam

    Departure
    Fri, Jan 29, 2027
    back Feb 19
    Length
    21 nights
    From Fort Lauderdale
    From$2,305per guestas of 4 hours ago
    View sailing
  19. Panama CanalCarnival Cruise Line

    13-Day Caribbean & Panama from Tampa, FL

    Carnival Legend

    Departure
    Sun, Jan 31, 2027
    back Feb 13
    Length
    13 nights
    From Tampa, FL
    Ports
    Grand Cayman, Cayman Islands · Limon, Costa Rica · Colón, Panama · Aruba · Curaçao
    From$1,212per guestas of 4 hours ago
    View sailing
  20. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Wed, Feb 3, 2027
    back Feb 15
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,934per guestas of 4 hours ago
    View sailing
  21. Panama CanalHolland America Line

    12-DAY PANAMA CANAL DISCOVERY: COSTA RICA & GREATER ANTILLES

    Nieuw Amsterdam

    Departure
    Sun, Feb 7, 2027
    back Feb 19
    Length
    12 nights
    From Fort Lauderdale
    From$1,588per guestas of 4 hours ago
    View sailing
  22. Panama CanalHolland America Line

    21-DAY PANAMA CANAL & SOUTHERN CARIBBEAN: ABC ISLANDS

    Nieuw Amsterdam

    Departure
    Sun, Feb 7, 2027
    back Feb 28
    Length
    21 nights
    From Fort Lauderdale
    From$2,426per guestas of 4 hours ago
    View sailing
  23. Panama CanalPrincess Cruises

    Panama Canal - Ocean to Ocean

    Island Princess

    Departure
    Sun, Feb 14, 2027
    back Mar 2
    Length
    16 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Panama Canal Full Transit Historic Locks · Fuerte Amador, Panama (for Panama City) · Puntarenas, Costa Rica · Puerto Chiapas, Mexico +2 more
    From$3,259per guestas of 4 hours ago
    View sailing
  24. Panama CanalPrincess Cruises

    Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departure
    Mon, Feb 15, 2027
    back Feb 27
    Length
    12 nights
    From Ft. Lauderdale, Florida
    Ports
    Aruba · Cartagena, Spain · Panama Canal Partial Transit New Locks · Colon · Limon, Costa Rica +1 more
    From$1,194per guestas of 9 days ago
    View sailing