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Cruises from Colon

40 cruises depart Colon, ranging from 7 to 10 nights. Prices start at $805. Most-visited destinations: Caribbean (23), Repositioning (1).

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Showing the first 24 of 40 sailings

  1. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Nov 14, 2026
    back Nov 24
    Length
    10 nights
    From Colon
    Ports
    Kralendijk · Oranjestad · Willemstad · Port of Spain · Scarborough
    From$1,339per guestas of 3 hours ago
    View sailing
  2. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Dec 26, 2026
    back Jan 2
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$3,345per guestas of 4 hours ago
    View sailing
  3. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 2, 2027
    back Jan 9
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,122per guestas of 4 hours ago
    View sailing
  4. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 9, 2027
    back Jan 16
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,611per guestas of 4 hours ago
    View sailing
  5. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 16, 2027
    back Jan 23
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,389per guestas of 4 hours ago
    View sailing
  6. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 23, 2027
    back Jan 30
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Santa Marta · Oranjestad · Willemstad
    From$1,313per guestas of 3 hours ago
    View sailing
  7. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 30, 2027
    back Feb 6
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Santa Marta · Oranjestad · Willemstad
    From$923per guestas of 3 hours ago
    View sailing
  8. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Feb 6, 2027
    back Feb 13
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,761per guestas of 4 hours ago
    View sailing
  9. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Feb 13, 2027
    back Feb 20
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Kralendijk
    From$1,138per guestas of 3 hours ago
    View sailing
  10. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Feb 20, 2027
    back Feb 27
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,632per guestas of 4 hours ago
    View sailing
  11. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Feb 27, 2027
    back Mar 6
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,192per guestas of 4 hours ago
    View sailing
  12. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Mar 6, 2027
    back Mar 13
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,131per guestas of 4 hours ago
    View sailing
  13. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Mar 13, 2027
    back Mar 20
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Kralendijk · Oranjestad · Willemstad
    From$1,110per guestas of 3 hours ago
    View sailing
  14. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Mar 20, 2027
    back Mar 27
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,182per guestas of 4 hours ago
    View sailing
  15. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Mar 27, 2027
    back Apr 3
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Kralendijk · Oranjestad · Willemstad
    From$992per guestas of 3 hours ago
    View sailing
  16. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Apr 3, 2027
    back Apr 10
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,037per guestas of 4 hours ago
    View sailing
  17. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Apr 10, 2027
    back Apr 17
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Kralendijk · Oranjestad · Willemstad
    From$1,212per guestas of 3 hours ago
    View sailing
  18. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Apr 17, 2027
    back Apr 24
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$942per guestas of 4 hours ago
    View sailing
  19. RepositioningRoyal Caribbean International

    Colon To San Juan Cruise

    Grandeur of the Seas

    Departure
    Sat, Apr 24, 2027
    back May 1
    Length
    7 nights
    From Colon
    Ports
    Kingstown · Castries · St. Johns · Tortola
    From$805per guestas of 3 hours ago
    View sailing
  20. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Dec 4, 2027
    back Dec 11
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,026per guestas of 4 hours ago
    View sailing
  21. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Dec 11, 2027
    back Dec 18
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,169per guestas of 4 hours ago
    View sailing
  22. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Dec 18, 2027
    back Dec 25
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,018per guestas of 4 hours ago
    View sailing
  23. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Dec 25, 2027
    back Jan 1
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$1,238per guestas of 4 hours ago
    View sailing
  24. CaribbeanRoyal Caribbean International

    Southern Caribbean Cruise

    Grandeur of the Seas

    Departure
    Sat, Jan 1, 2028
    back Jan 8
    Length
    7 nights
    From Colon
    Ports
    Cartagena · Oranjestad · Willemstad
    From$866per guestas of 4 hours ago
    View sailing
See all 40 sailings

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