← Back to search

Panama CanalRoyal Caribbean International

Panama Canal Eastward Cruise

Serenade of the Seas15 nightsThu, Oct 7, 2027 → Fri, Oct 22, 2027Departs San Diego

Starting from

$1,899

per guest, double occupancy · taxes & fees may applyas of 16 hours ago

Book on Royal Caribbean International

We may earn a commission when you book through this link. No added cost to you.

Day-by-day itinerary

Day1
San Diego(SAN)
Depart 5:00 PM
Day2
Day at sea
Day3
Day at sea
Day4
Puerto Vallarta(PVR)
Arrive 8:00 AMDepart 5:00 PM
Day5
Day at sea
Day6
Day at sea
Day7
Puerto Quetzal(GUA)
Arrive 8:00 AMDepart 5:00 PM
Day8
Day at sea
Day9
Puntarenas(SJO)
Arrive 8:00 AMDepart 5:00 PM
Day10
Day at sea
Day11
Panama Canal (Cruising)(PTY)
Arrive 6:00 AMDepart 6:00 PM
Day12
Cartagena(CTG)
Arrive 11:30 AMDepart 7:00 PM
Day13
Day at sea
Day14
George Town(GCM)
Arrive 7:00 AMDepart 4:00 PM
Day15
Day at sea
Day16
Tampa(TPA)
Arrive 5:00 AM

Cabin categories

3 of 4 available

Category	Type	From	Action
INTERIOR INTERIOR	Interior	$1,899	Book
OUTSIDE OUTSIDE	Oceanview	$2,249	Book
BALCONY BALCONY	Balcony	$3,549	Book
DELUXE DELUXE	Suite	Sold out

More from Serenade of the Seas

AlaskaRoyal Caribbean International
Alaska Inside Passage Cruise
Serenade of the Seas
Departure
Sun, Jun 14, 2026
back Jun 21
Length
7 nights
From Vancouver
Ports
Inside Passage · Sitka · Endicott Arm & Dawes Glacier
From$1,349per guestas of 16 hours ago
View sailing
AlaskaRoyal Caribbean International
Alaska Inside Passage Cruise
Serenade of the Seas
Departure
Sun, Jun 21, 2026
back Jun 28
Length
7 nights
From Vancouver
Ports
Inside Passage · Sitka · Endicott Arm & Dawes Glacier
From$7,178per guestas of 16 hours ago
View sailing
AlaskaRoyal Caribbean International
Alaska Inside Passage Cruise
Serenade of the Seas
Departure
Sun, Jun 28, 2026
back Jul 5
Length
7 nights
From Vancouver
Ports
Inside Passage · Sitka · Endicott Arm & Dawes Glacier
From$1,623per guestas of 16 hours ago
View sailing